hmg-3 - Caenorhabditis elegans (Gene:172250) - DAnCER - Wodak Lab

Description

HMG

Species

Caenorhabditis elegans

Chromosome

I

CM Evidence

CM Status: Putative

Enzymatic Function

GO Annotations

GO biological process and molecular function terms related to CM are highlighted in red.

Molecular function

GO:0003677: DNA binding (IEA)
Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).
Annotated on O01683 with IEA (UniProtKB-KW:KW-0238)

Biological process

GO:0000003: reproduction (IMP)
The production by an organism of new individuals that contain some portion of their genetic material inherited from that organism.
Annotated on O01683 with IMP (WB:WBRNAi00085750)
GO:0000910: cytokinesis (IMP)
A cellular process resulting in the division of the cytoplasm of a cell and its separation into two daughter cells. Cytokinesis usually occurs after growth, replication, and segregation of cellular components.
Annotated on O01683 with IMP (WB:WBRNAi00007788)
GO:0002119: nematode larval development (IMP)
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
Annotated on O01683 with IMP (WB:WBRNAi00024707)
GO:0006260: DNA replication (IEA)
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
Annotated on O01683 with IEA (UniProtKB-KW:KW-0235)
GO:0006281: DNA repair (IEA)
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
Annotated on O01683 with IEA (UniProtKB-KW:KW-0234)
GO:0006351: transcription, DNA-dependent (IEA)
The cellular synthesis of RNA on a template of DNA.
Annotated on O01683 with IEA (UniProtKB-KW:KW-0804)
GO:0006355: regulation of transcription, DNA-dependent (IEA)
Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription.
Annotated on O01683 with IEA (UniProtKB-KW:KW-0805)
GO:0006974: response to DNA damage stimulus (IEA)
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
Annotated on O01683 with IEA (UniProtKB-KW:KW-0227)
GO:0007413: axonal fasciculation (IMP)
The collection of axons into a bundle of rods, known as a fascicle.
Annotated on O01683 with IMP (WB:WBRNAi00066064)
GO:0009792: embryo development ending in birth or egg hatching (IMP)
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
Annotated on O01683 with IMP (WB:WBRNAi00024708)
GO:0010171: body morphogenesis (IMP)
The process in which the anatomical structures of the soma are generated and organized.
Annotated on O01683 with IMP (WB:WBRNAi00024707)
GO:0040007: growth (IMP)
The increase in size or mass of an entire organism, a part of an organism or a cell.
Annotated on O01683 with IMP (WB:WBRNAi00024707)
GO:0040010: positive regulation of growth rate (IMP)
Any process that increases the rate of growth of all or part of an organism.
Annotated on O01683 with IMP (WB:WBRNAi00066064)
GO:0040011: locomotion (IMP)
Self-propelled movement of a cell or organism from one location to another.
Annotated on O01683 with IMP (WB:WBRNAi00066064)
GO:0040018: positive regulation of multicellular organism growth (IMP)
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
Annotated on O01683 with IMP (WB:WBRNAi00024707)
GO:0048477: oogenesis (IMP)
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
Annotated on O01683 with IMP (WB:WBRNAi00085750)
GO:0051301: cell division (IMP)
The process resulting in the physical partitioning and separation of a cell into daughter cells.
Annotated on O01683 with IMP (WB:WBRNAi00007788)

Cellular component

GO:0005634: nucleus (IEA)
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
Annotated on O01683 with IEA (UniProtKB-SubCell:SL-0191)
GO:0005694: chromosome (IEA)
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
Annotated on O01683 with IEA (UniProtKB-SubCell:SL-0468)

CORUM Complexes

Not a member of any complex.

Interactions

Interacting Proteinhmg-3's ProteinSupporting PublicationsInteraction
O62332_CAEEL (O62332) SSP1B_CAEEL 1 iRef:1218659

Domains

Domains
Float your mouse over the coloured bars to see the domain name and sequence position. PFAM A is above the black line, PFAM B below.
DAnCER 2.3
Disease Annotated Chromatin Epigenetics Resource